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Anti-FBP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05912
Anti-FBP1 Polyclonal Antibody is a Rabbit antibody targeting FBP1. Anti-FBP1 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Anti-FBP1 Polyclonal Antibody
Anti-FBP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05912
Anti-FBP1 Polyclonal Antibody is a Rabbit antibody targeting FBP1. Anti-FBP1 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-FBP1 Polyclonal Antibody is a Rabbit antibody targeting FBP1. Anti-FBP1 Polyclonal Antibody can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Pig,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytosol;Extracellular region or secreted;Nucleus |
| Tissue Specificity | Belongs to the FBPase class 1 family. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human FBP1 |
| Antigen Species | Human |
| Gene Name | FBP1 |
| Gene ID | |
| Protein Name | Fructose-1, 6-bisphosphatase 1 |
| Uniprot ID | |
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. |
| Molecular Weight | Theoretical: 37 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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