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Anti-MMP8 Polyclonal Antibody

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Catalog No. TMAB-08881

Anti-MMP8 Polyclonal Antibody is a Rabbit antibody targeting MMP8. Anti-MMP8 Polyclonal Antibody can be used in WB.

Anti-MMP8 Polyclonal Antibody

Anti-MMP8 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-08881
Anti-MMP8 Polyclonal Antibody is a Rabbit antibody targeting MMP8. Anti-MMP8 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MMP8 Polyclonal Antibody is a Rabbit antibody targeting MMP8. Anti-MMP8 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
Sample:
Lane 1: Mouse Bone marrow Lysates
Lane 2: Mouse Spleen Lysates
Lane 3: Mouse Uterus Lysates
Lane 4: Mouse Testis Lysates
Lane 5: Mouse NIH/3T3 cell Lysates
Lane 6: Rat Bone marrow Lysates
Lane 7: Rat Spleen Lysates
Lane 8: Rat Uterus Lysates
Lane 9: Rat Testis Lysates
Lane 10: Human Jurkat cell Lysates
Lane 11: Human A549 cell Lysates
Lane 12: Human HL-60 cell Lysates
Lane 13: Human MCF-7 cell Lysates
Lane 14: Human HepG2 cell Lysates
Primary: Anti-MMP8 (TMAB-08881) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kDa
Observed band size: 60 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic granule. Secreted, extracellular space, extracellular matrix (Probable). Note=Stored in intracellular granules.
Tissue SpecificityNeutrophils.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MMP8
Antigen Species
Human
Gene Name
MMP8
Gene ID
Protein Name
Neutrophil collagenase
Uniprot ID
Function
Can degrade fibrillar type I, II, and III collagens.
Chemical Properties
Molecular WeightTheoretical: 38 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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