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Anti-MMP8 Polyclonal Antibody is a Rabbit antibody targeting MMP8. Anti-MMP8 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
| Description | Anti-MMP8 Polyclonal Antibody is a Rabbit antibody targeting MMP8. Anti-MMP8 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse Bone marrow Lysates Lane 2: Mouse Spleen Lysates Lane 3: Mouse Uterus Lysates Lane 4: Mouse Testis Lysates Lane 5: Mouse NIH/3T3 cell Lysates Lane 6: Rat Bone marrow Lysates Lane 7: Rat Spleen Lysates Lane 8: Rat Uterus Lysates Lane 9: Rat Testis Lysates Lane 10: Human Jurkat cell Lysates Lane 11: Human A549 cell Lysates Lane 12: Human HL-60 cell Lysates Lane 13: Human MCF-7 cell Lysates Lane 14: Human HepG2 cell Lysates Primary: Anti-MMP8 (TMAB-08881) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kDa Observed band size: 60 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic granule. Secreted, extracellular space, extracellular matrix (Probable). Note=Stored in intracellular granules. |
| Tissue Specificity | Neutrophils. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human MMP8 |
| Antigen Species | Human |
| Gene Name | MMP8 |
| Gene ID | |
| Protein Name | Neutrophil collagenase |
| Uniprot ID | |
| Function | Can degrade fibrillar type I, II, and III collagens. |
| Molecular Weight | Theoretical: 38 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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