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Anti-FLVCR Polyclonal Antibody

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Catalog No. TMAB-06082

Anti-FLVCR Polyclonal Antibody is a Rabbit antibody targeting FLVCR. Anti-FLVCR Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-FLVCR Polyclonal Antibody

Anti-FLVCR Polyclonal Antibody

😃Good
Catalog No. TMAB-06082
Anti-FLVCR Polyclonal Antibody is a Rabbit antibody targeting FLVCR. Anti-FLVCR Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FLVCR Polyclonal Antibody is a Rabbit antibody targeting FLVCR. Anti-FLVCR Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Pig,Horse)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
Tissue SpecificityFound all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFLVCR is responsible for the exportation of cytoplasmic heme groups. It is believed that it may protect developing erythroid cells from heme toxicity. Expression of FLVCR in cells will cause susceptibility to FeLV-C (Feline leukemia virus subgroup C) in vitro. FLVCR is found in all hematopoietic tissues, including peripheral blood lymphocytes and fetal liver, and some expression is found in pancreas and kidney. It is down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: Human FLVCR
Antigen Species
Human
Gene Name
FLVCR1
Gene ID
Protein Name
Feline leukemia virus subgroup C receptor-related protein 1
Uniprot ID
Function
Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and may be required to protect developing erythroid cells from heme toxicity. Heme export also provides protection from heme or ferrous iron toxicities in liver and brain. Causes susceptibility to FeLV-C in vitro.
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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