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Anti-LGALS3BP Polyclonal Antibody
Catalog No. TMAB-08286 Copy Product Info
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Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Anti-LGALS3BP Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08286
Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Anti-LGALS3BP Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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| Description | Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. 25 μg total protein per lane of various lysates (see on figure) probed with LGALS3BP polyclonal antibody, unconjugated (TMAB-08286) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. 2. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LGALS3BP Polyclonal Antibody, Unconjugated (TMAB-08286) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LGALS3BP Polyclonal Antibody, Unconjugated (TMAB-08286) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LGALS3BP Polyclonal Antibody, Unconjugated (TMAB-08286) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LGALS3BP Polyclonal Antibody, Unconjugated (TMAB-08286) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LGALS3BP Polyclonal Antibody, Unconjugated (TMAB-08286) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | LGALS3BP is a ligand of galectin 3, and has been suggested to influence tumor proliferation and metastasis formation. Galectins and their ligands have been implicated in cell transformation and cancer metastasis, and found to have prognostic value. LGALS3BP also known as Mac 2 BP,and as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin 1, galectin 3 and galectin 7. High expression levels of this molecule are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy in patients with different types of malignancy. The mechanisms underlying the prognostic significance of 90K and galectins in cancer are far from being understood, although they may be related to the ability of these proteins to interact and, to some extent, modulate cell cell and cell matrix adhesion and apoptosis. |
| Immunogen | KLH conjugated synthetic peptide: human LGALS3BP |
| Antigen Species | Human |
| Gene Name | LGALS3BP |
| Gene ID | |
| Protein Name | Galectin-3-binding protein |
| Uniprot ID | |
| Function | Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
| Molecular Weight | Theoretical: 63 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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