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Anti-LGALS3BP Polyclonal Antibody
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Catalog No. TMAB-08286
Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Anti-LGALS3BP Polyclonal Antibody
Anti-LGALS3BP Polyclonal Antibody
😃Good
Catalog No. TMAB-08286
Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | LGALS3BP is a ligand of galectin 3, and has been suggested to influence tumor proliferation and metastasis formation. Galectins and their ligands have been implicated in cell transformation and cancer metastasis, and found to have prognostic value. LGALS3BP also known as Mac 2 BP,and as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin 1, galectin 3 and galectin 7. High expression levels of this molecule are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy in patients with different types of malignancy. The mechanisms underlying the prognostic significance of 90K and galectins in cancer are far from being understood, although they may be related to the ability of these proteins to interact and, to some extent, modulate cell cell and cell matrix adhesion and apoptosis. |
| Immunogen | KLH conjugated synthetic peptide: human LGALS3BP |
| Antigen Species | Human |
| Gene Name | LGALS3BP |
| Gene ID | |
| Protein Name | Galectin-3-binding protein |
| Uniprot ID | |
| Function | Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
| Molecular Weight | Theoretical: 63 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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