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Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody
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Catalog No. TMAB-10273
Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-Myc (Thr58/Ser62). Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody
Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody
😃Good
Catalog No. TMAB-10273
Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-Myc (Thr58/Ser62). Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-Myc (Thr58/Ser62). Anti-Phospho-C-Myc (Thr58/Ser62) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus, nucleoplasm. |
| Tissue Specificity | Low levels detected throughout embryo before cellular blastoderm formation, particularly concentrated in pole plasm. Zygotic expression detected during cellular blastoderm stage in endodermal anlagen of anterior and posterior midgut at both poles. After gastrulation, expression detected in invaginating ventral furrow of mesoderm. Continued expression in anterior and posterior midgut and mesoderm during germband extension. During late germ-band retraction, expression remains detectable in fusing midgut and presumed developing somatic musculature. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human c-Myc around the phosphorylation site of Thr58 and Ser62 |
| Antigen Species | Human |
| Gene Name | MYC |
| Gene ID | |
| Protein Name | Myc proto-oncogene protein |
| Uniprot ID | |
| Function | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. |
| Molecular Weight | Theoretical: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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