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Anti-CFC1 Polyclonal Antibody
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Catalog No. TMAB-04266
Anti-CFC1 Polyclonal Antibody is a Rabbit antibody targeting CFC1. Anti-CFC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-CFC1 Polyclonal Antibody
Anti-CFC1 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-04266
Anti-CFC1 Polyclonal Antibody is a Rabbit antibody targeting CFC1. Anti-CFC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CFC1 Polyclonal Antibody is a Rabbit antibody targeting CFC1. Anti-CFC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Human glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CFC1) Polyclonal Antibody, Unconjugated (TMAB-04266) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Protein: Hela (human) lysate at 40 μg; Primary: rabbit Anti-CFC1 (TMAB-04266) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1: 5000; Predicted band size: 15 kD Observed band size: 15 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Secreted. Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| Immunogen | KLH conjugated synthetic peptide: human CFC1 |
| Antigen Species | Human |
| Gene Name | CFC1 |
| Gene ID | |
| Protein Name | Cryptic protein |
| Uniprot ID | |
| Function | NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. |
| Molecular Weight | Theoretical: 15 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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