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Anti-NIS Polyclonal Antibody

Catalog No. TMAB-09489 Copy Product Info
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Anti-NIS Polyclonal Antibody is a Rabbit antibody targeting NIS. Anti-NIS Polyclonal Antibody can be used in WB.

Anti-NIS Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09489

Anti-NIS Polyclonal Antibody is a Rabbit antibody targeting NIS. Anti-NIS Polyclonal Antibody can be used in WB.

Anti-NIS Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NIS Polyclonal Antibody is a Rabbit antibody targeting NIS. Anti-NIS Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample: U937 (Human) Cell Lysate at 30 μg
Primary: Anti-NIS (TMAB-09489) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 68 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityExpression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Backgroundcatalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation. Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NIS
Antigen Species
Human
Gene Name
SLC5A5
Gene ID
Protein Name
Sodium/iodide cotransporter
Uniprot ID
Function
Mediates iodide uptake in the thyroid gland.
Chemical Properties
Molecular WeightTheoretical: 68 kDa. Actual: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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