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Anti-ZC3H13 Polyclonal Antibody
Catalog No. TMAB-14257 Copy Product Info
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Anti-ZC3H13 Polyclonal Antibody is a Rabbit antibody targeting ZC3H13. Anti-ZC3H13 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-ZC3H13 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-14257
Anti-ZC3H13 Polyclonal Antibody is a Rabbit antibody targeting ZC3H13. Anti-ZC3H13 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-ZC3H13 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ZC3H13 Polyclonal Antibody is a Rabbit antibody targeting ZC3H13. Anti-ZC3H13 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ZC3H13) Polyclonal Antibody, Unconjugated (TMAB-14257) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Contains 1 C3H1-type zinc finger. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ZC3H13 is a 1668 amino acid protein that contains one C3H1-type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Immunogen | KLH conjugated synthetic peptide: human ZC3H13 |
| Antigen Species | Human |
| Gene Name | ZC3H13 |
| Gene ID | |
| Protein Name | Zinc finger CCCH domain-containing protein 13 |
| Uniprot ID |
| Molecular Weight | Theoretical: 196 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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