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Anti-PIAS1 Polyclonal Antibody
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Catalog No. TMAB-11431
Anti-PIAS1 Polyclonal Antibody is a Rabbit antibody targeting PIAS1. Anti-PIAS1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-PIAS1 Polyclonal Antibody
Anti-PIAS1 Polyclonal Antibody
😃Good
Catalog No. TMAB-11431
Anti-PIAS1 Polyclonal Antibody is a Rabbit antibody targeting PIAS1. Anti-PIAS1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PIAS1 Polyclonal Antibody is a Rabbit antibody targeting PIAS1. Anti-PIAS1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus speckle. Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton. |
| Tissue Specificity | Expressed in numerous tissues with highest level in testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Immunogen | KLH conjugated synthetic peptide: human PIAS1 |
| Antigen Species | Human |
| Gene Name | PIAS1 |
| Gene ID | |
| Protein Name | E3 SUMO-protein ligase PIAS1 |
| Uniprot ID | |
| Function | Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Together with PRMT1, may repress STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. |
| Molecular Weight | Theoretical: 81 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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