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MRS-3777 hemioxalate

🥰Excellent
Catalog No. T12107Cas No. 1186195-57-2

MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.

MRS-3777 hemioxalate

MRS-3777 hemioxalate

🥰Excellent
Purity: 97.10%
Catalog No. T12107Cas No. 1186195-57-2
MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$69-In Stock
5 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:97.10%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.
Chemical Properties
Molecular Weight354.39
FormulaC17H19N5O.1/2C2H2O4
Cas No.1186195-57-2
SmilesO=C(O)C(=O)O.N1=CNC2=C1N=C(N=C2NC3CCCCC3)OC=4C=CC=CC4 0.5 Oxalic Acid
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (225.74 mM), Sonication is recommended.
H2O: <0.1 mg/mL (insoluble)
In Vivo Formulation
10% DMSO+90% Corn Oil: 3.3 mg/mL (9.31 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8218 mL14.1088 mL28.2175 mL141.0875 mL
5 mM0.5644 mL2.8218 mL5.6435 mL28.2175 mL
10 mM0.2822 mL1.4109 mL2.8218 mL14.1088 mL
20 mM0.1411 mL0.7054 mL1.4109 mL7.0544 mL
50 mM0.0564 mL0.2822 mL0.5644 mL2.8218 mL
100 mM0.0282 mL0.1411 mL0.2822 mL1.4109 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MRS-3777 HemioxalateMRS-3777MRS3777MRS 3777AdenosineReceptorAdenosine Receptoradenosine A3 receptorA3
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