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Anti-HELZ Polyclonal Antibody
😃Good
Catalog No. TMAB-06965
Anti-HELZ Polyclonal Antibody is a Rabbit antibody targeting HELZ. Anti-HELZ Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-HELZ Polyclonal Antibody
Anti-HELZ Polyclonal Antibody
😃Good
Catalog No. TMAB-06965
Anti-HELZ Polyclonal Antibody is a Rabbit antibody targeting HELZ. Anti-HELZ Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HELZ Polyclonal Antibody is a Rabbit antibody targeting HELZ. Anti-HELZ Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus (Probable). |
| Tissue Specificity | Expressed predominantly in thymus and brain. Expression is down-regulated in 28 of 95 tested cancer cell lines. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Helicases comprise a class of enzymes that function as motor proteins which move along nucleic acid phosphodiester bonds, effectively separating two annealed nucleic acid strands. RNA helicases alter the conformation of RNA, specifically by unwinding double-stranded RNA regions to yield single RNA strands, a process which changes the biological activity of the RNA molecule. HELZ (helicase with zinc finger), also known as DHRC or HUMORF5, is a 1,942 amino acid nuclear protein that contains one C3H1-type zinc finger and belongs to the RNA helicase superfamily. Expressed ubiquitously during embryonic development, HELZ is thought to function as an RNA helicase that modifies RNA structure and plays a role in the development of multiple organs and tissues within the developing embryo. |
| Immunogen | KLH conjugated synthetic peptide: human HELZ |
| Antigen Species | Human |
| Gene Name | HELZ |
| Gene ID | |
| Protein Name | Probable helicase with zinc finger domain |
| Uniprot ID | |
| Function | May act as a helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo. |
| Molecular Weight | Theoretical: 219 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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