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Anti-MAGI3 Polyclonal Antibody

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Catalog No. TMAB-08528

Anti-MAGI3 Polyclonal Antibody is a Rabbit antibody targeting MAGI3. Anti-MAGI3 Polyclonal Antibody can be used in WB.

Anti-MAGI3 Polyclonal Antibody

Anti-MAGI3 Polyclonal Antibody

😃Good
Catalog No. TMAB-08528
Anti-MAGI3 Polyclonal Antibody is a Rabbit antibody targeting MAGI3. Anti-MAGI3 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MAGI3 Polyclonal Antibody is a Rabbit antibody targeting MAGI3. Anti-MAGI3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Cell junction > tight junction. Nucleus. Concentrates in specific sites at the plasma membrane and in the nucleus. In epithelial cells, it localizes at tight junctions.
Tissue SpecificityWidely expressed.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMAGE-H1 is a 219 amino acid protein that contains a type II MAGE homology domain (MHD). Enhanced ligand stimulation promotes MAGE-H1 interaction with the type II death domain of NGFR p75. It is suggested that MAGE-H1 accelerates differentiation in response to nerve growth factor in cells.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MAGI3
Antigen Species
Human
Gene Name
Magi3
Gene ID
260425
Protein Name
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
Uniprot ID
Q5TCQ9
Function
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
Chemical Properties
Molecular WeightTheoretical: 166 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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