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Anti-Jagged1/CD339 Polyclonal Antibody

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Catalog No. TMAB-07855

Anti-Jagged1/CD339 Polyclonal Antibody is a Rabbit antibody targeting Jagged1/CD339. Anti-Jagged1/CD339 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Jagged1/CD339 Polyclonal Antibody

Anti-Jagged1/CD339 Polyclonal Antibody

😃Good
Catalog No. TMAB-07855
Anti-Jagged1/CD339 Polyclonal Antibody is a Rabbit antibody targeting Jagged1/CD339. Anti-Jagged1/CD339 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Jagged1/CD339 Polyclonal Antibody is a Rabbit antibody targeting Jagged1/CD339. Anti-Jagged1/CD339 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
Tissue SpecificityWidely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Jagged1/CD339
Antigen Species
Human
Gene Name
JAG1
Gene ID
182
Protein Name
Protein jagged-1
Uniprot ID
P78504
Function
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Chemical Properties
Molecular WeightTheoretical: 134 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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