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Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody
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Catalog No. TMAB-10713
Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32). Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody can be used in FCM.
Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody
Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody
😃Good
Catalog No. TMAB-10713
Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32). Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32). Anti-Phospho-FOXO1+FOXO3+FOXO4 (Thr24+Thr32) Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | FCM: 2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus. Translocates to the nucleus upon oxidative stress induced phosphorylation at Ser-212 by STK4/MST1. Translocates to the nucleus upon phosphorylation of Thr-24, Ser-256 and Ser-322 by SGK1. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq]. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human FOXO1 around the phosphorylation site of Thr24 |
| Antigen Species | Human |
| Gene Name | FOXO1 |
| Gene ID | |
| Protein Name | Forkhead box protein O1 |
| Uniprot ID | |
| Function | Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. Triggers death of postmitotic neurons when phosphorylated by CDK1. Activates transcription of PMAIP1. |
| Molecular Weight | Theoretical: 74 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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