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Anti-MX1 Polyclonal Antibody

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Catalog No. TMAB-09128

Anti-MX1 Polyclonal Antibody is a Rabbit antibody targeting MX1. Anti-MX1 Polyclonal Antibody can be used in WB.

Anti-MX1 Polyclonal Antibody

Anti-MX1 Polyclonal Antibody

😃Good
Catalog No. TMAB-09128
Anti-MX1 Polyclonal Antibody is a Rabbit antibody targeting MX1. Anti-MX1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MX1 Polyclonal Antibody is a Rabbit antibody targeting MX1. Anti-MX1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Dog)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space. Nucleus. Note=Translocates into the nuclei of HSV-1 infected cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Backgroundbs-6653P is onesynthetic peptide derived from human MX1. The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-alpha/IFN-beta. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-alpha/IFN-beta, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MX1
Antigen Species
Human
Gene Name
MX1
Gene ID
4599
Protein Name
MX dynamin like GTPase 1
Uniprot ID
P20591
Function
May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus.
Chemical Properties
Molecular WeightTheoretical: 73/79 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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