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Anti-MGLUR3 Polyclonal Antibody
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Catalog No. TMAB-08792
Anti-MGLUR3 Polyclonal Antibody is a Rabbit antibody targeting MGLUR3. Anti-MGLUR3 Polyclonal Antibody can be used in WB,FCM.
Anti-MGLUR3 Polyclonal Antibody
Anti-MGLUR3 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-08792
Anti-MGLUR3 Polyclonal Antibody is a Rabbit antibody targeting MGLUR3. Anti-MGLUR3 Polyclonal Antibody can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-MGLUR3 Polyclonal Antibody is a Rabbit antibody targeting MGLUR3. Anti-MGLUR3 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Cow,Horse,Rabbit) |
| Verified Activity | 1. Blank control: Mouse Liver Cells (fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice). Primary Antibody: Rabbit Anti-MGLUR3/PE Conjugated antibody (TMAB-08792-PE), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/Pe (orange), used under the same conditions. 2. Sample: Hippocampus (Mouse) Lysate at 40 μg Primary: Anti-MGLUR3 (TMAB-08792) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 96 kD Observed band size: 116 kD 3. Sample: Cerebral cortex (Mouse) Lysate at 40 μg Primary: Anti-MGLUR3 (TMAB-08792) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 96 kD Observed band size: 116 kD 4. Sample: Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-MGLUR3 (TMAB-08792) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 96 kD Observed band size: 116 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 5μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution. |
| Immunogen | KLH conjugated synthetic peptide: human Metabotropic Glutamate Receptor 3 |
| Antigen Species | Human |
| Gene Name | GRM3 |
| Gene ID | |
| Protein Name | Metabotropic glutamate receptor 3 |
| Uniprot ID | |
| Function | Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. |
| Molecular Weight | Theoretical: 96 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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