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Anti-MGLUR3 Polyclonal Antibody

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Catalog No. TMAB-08792

Anti-MGLUR3 Polyclonal Antibody is a Rabbit antibody targeting MGLUR3. Anti-MGLUR3 Polyclonal Antibody can be used in WB,FCM.

Anti-MGLUR3 Polyclonal Antibody

Anti-MGLUR3 Polyclonal Antibody

😃Good
Catalog No. TMAB-08792
Anti-MGLUR3 Polyclonal Antibody is a Rabbit antibody targeting MGLUR3. Anti-MGLUR3 Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MGLUR3 Polyclonal Antibody is a Rabbit antibody targeting MGLUR3. Anti-MGLUR3 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Cow,Horse,Rabbit)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 5μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Metabotropic Glutamate Receptor 3
Antigen Species
Human
Gene Name
GRM3
Gene ID
2913
Protein Name
Metabotropic glutamate receptor 3
Uniprot ID
Q14832
Function
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
Chemical Properties
Molecular WeightTheoretical: 96 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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