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Anti-Alpha-actinin-1 Polyclonal Antibody

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Catalog No. TMAB-02487

Anti-Alpha-actinin-1 Polyclonal Antibody is a Rabbit antibody targeting Alpha-actinin-1. Anti-Alpha-actinin-1 Polyclonal Antibody can be used in WB.

Anti-Alpha-actinin-1 Polyclonal Antibody

Anti-Alpha-actinin-1 Polyclonal Antibody

😃Good
Catalog No. TMAB-02487
Anti-Alpha-actinin-1 Polyclonal Antibody is a Rabbit antibody targeting Alpha-actinin-1. Anti-Alpha-actinin-1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Alpha-actinin-1 Polyclonal Antibody is a Rabbit antibody targeting Alpha-actinin-1. Anti-Alpha-actinin-1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human Alpha-actinin-1 protein
Antigen Species
Human
Gene Name
ACTN1
Gene ID
87
Protein Name
alpha-actinin-1
Uniprot ID
P12814
Function
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Chemical Properties
Molecular WeightTheoretical: 103 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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