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Antibacterialagent 206 (Compound 10e) is an oxanthracene compound derived from indole acryl derivatives, exhibiting a broad antibacterial spectrum with a MIC of 0.25-1 μg/mL. It reduces extracellular polysaccharides and disrupts biofilms, thus mitigating resistance. Its antibacterial effects are achieved by compromising membrane integrity, accumulating reactive oxygen species (ROS), and inhibiting DNA replication.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Backorder | Backorder | |
| 50 mg | Inquiry | Backorder | Backorder |
| Description | Antibacterialagent 206 (Compound 10e) is an oxanthracene compound derived from indole acryl derivatives, exhibiting a broad antibacterial spectrum with a MIC of 0.25-1 μg/mL. It reduces extracellular polysaccharides and disrupts biofilms, thus mitigating resistance. Its antibacterial effects are achieved by compromising membrane integrity, accumulating reactive oxygen species (ROS), and inhibiting DNA replication. |
| In vitro | Antibacterial agent 206 demonstrates antibacterial properties against Enterococcus, Staphylococcus, Escherichia, Acinetobacter, and Pseudomonas strains, with a minimum inhibitory concentration (MIC) ranging from 0.25 to 1 μg/mL. Within the range of 0-256 μg/mL, Antibacterial agent 206 exhibits low hemolytic activity, minimal cytotoxicity towards blood, human liver cells (LO2), and HUVECs, and shows good compatibility with red blood cells. |
| Formula | C30H28FN5O5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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