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Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody
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Catalog No. TMAB-11167
Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCB3 (Ser1105). Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody can be used in ICC/IF,FCM.
Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody
Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody
😃Good
Catalog No. TMAB-11167
Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCB3 (Ser1105). Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody can be used in ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCB3 (Ser1105). Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody can be used in ICC/IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse) |
| Application | |
| Recommended Dose | ICC/IF: 1:100-500; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Peripheral membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human PLC beta3 around the phosphorylation site of Ser1105 |
| Antigen Species | Human |
| Gene Name | PLCB3 |
| Gene ID | |
| Protein Name | 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-3 |
| Uniprot ID | |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. |
| Molecular Weight | Theoretical: 136 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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