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Anti-HRC Polyclonal Antibody
Catalog No. TMAB-07287 Copy Product Info
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Anti-HRC Polyclonal Antibody is a Rabbit antibody targeting HRC. Anti-HRC Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HRC Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07287
Anti-HRC Polyclonal Antibody is a Rabbit antibody targeting HRC. Anti-HRC Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HRC Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HRC Polyclonal Antibody is a Rabbit antibody targeting HRC. Anti-HRC Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (human heart tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (HRC) Polyclonal Antibody, Unconjugated (TMAB-07287) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Sarcoplasmic reticulum lumen. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | HRC is a 699 amino acid that binds low-density lipoprotein with high affinity. As a high capacity calcium binding protein, HRC regulates the sequestration and release of calcium in the lumen of the junctional sarcoplasmic reticulum (SR) of cardiac, skeletal and smooth muscle. This mechanism may involve direct interaction between HRC and the cytoplasmic domain of Triadin, an integral membrane protein of the SR. The gene encoding HRC maps to human chromosome 19q13.33 and mouse chromosome 7 B4 |
| Immunogen | KLH conjugated synthetic peptide: human HRC |
| Antigen Species | Human |
| Gene Name | HRC |
| Gene ID | |
| Protein Name | Sarcoplasmic reticulum histidine-rich calcium-binding protein |
| Uniprot ID | |
| Function | May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. |
| Molecular Weight | Theoretical: 77 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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