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Anti-RNF170 Polyclonal Antibody

Catalog No. TMAB-12307 Copy Product Info
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Anti-RNF170 Polyclonal Antibody is a Rabbit antibody targeting RNF170. Anti-RNF170 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-RNF170 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12307

Anti-RNF170 Polyclonal Antibody is a Rabbit antibody targeting RNF170. Anti-RNF170 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-RNF170 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RNF170 Polyclonal Antibody is a Rabbit antibody targeting RNF170. Anti-RNF170 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (rat testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (RNF170) Polyclonal Antibody, Unconjugated (TMAB-12307) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (RNF170) Polyclonal Antibody, Unconjugated (TMAB-12307) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein (By similarity).
Tissue SpecificityExpressed in the spinal chord.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe ring finger is a specialized type of zinc finger of 40 to 60 residues that binds two atoms of zinc and mediates protein-protein interactions. There are five known isoforms of RNF170.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human RNF170
Antigen Species
Human
Gene Name
RNF170
Gene ID
81790
Protein Name
E3 ubiquitin-protein ligase RNF170
Uniprot ID
Q96K19
Function
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.
Chemical Properties
Molecular WeightTheoretical: 30 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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