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Anti-CCR2+CCR5 Polyclonal Antibody

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Catalog No. TMAB-03798

Anti-CCR2+CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR2+CCR5. Anti-CCR2+CCR5 Polyclonal Antibody can be used in WB.

Anti-CCR2+CCR5 Polyclonal Antibody

Anti-CCR2+CCR5 Polyclonal Antibody

😃Good
Catalog No. TMAB-03798
Anti-CCR2+CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR2+CCR5. Anti-CCR2+CCR5 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CCR2+CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR2+CCR5. Anti-CCR2+CCR5 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Horse)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityDetected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse CCR2 and CCR5
Antigen Species
Mouse
Gene Name
CCR2
Gene ID
Protein Name
C-C chemokine receptor type 2
Uniprot ID
Function
Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Chemical Properties
Molecular WeightTheoretical: 43 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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