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Anti-Dio3 Polyclonal Antibody
😃Good
Catalog No. TMAB-05164
Anti-Dio3 Polyclonal Antibody is a Rabbit antibody targeting Dio3. Anti-Dio3 Polyclonal Antibody can be used in WB.
Anti-Dio3 Polyclonal Antibody
Anti-Dio3 Polyclonal Antibody
😃Good
Catalog No. TMAB-05164
Anti-Dio3 Polyclonal Antibody is a Rabbit antibody targeting Dio3. Anti-Dio3 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Dio3 Polyclonal Antibody is a Rabbit antibody targeting Dio3. Anti-Dio3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed in placenta and several fetal tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults. |
| Immunogen | KLH conjugated synthetic peptide: human Dio3 |
| Antigen Species | Human |
| Gene Name | DIO3 |
| Gene ID | |
| Protein Name | Thyroxine 5-deiodinase |
| Uniprot ID |
| Molecular Weight | Theoretical: 31 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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