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Anti-Integrin alpha-3 heavy chain Polyclonal Antibody
😃Good
Catalog No. TMAB-07747
Anti-Integrin alpha-3 heavy chain Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha-3 heavy chain. Anti-Integrin alpha-3 heavy chain Polyclonal Antibody can be used in WB.
Anti-Integrin alpha-3 heavy chain Polyclonal Antibody
Anti-Integrin alpha-3 heavy chain Polyclonal Antibody
😃Good
Catalog No. TMAB-07747
Anti-Integrin alpha-3 heavy chain Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha-3 heavy chain. Anti-Integrin alpha-3 heavy chain Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Integrin alpha-3 heavy chain Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha-3 heavy chain. Anti-Integrin alpha-3 heavy chain Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Integrin alpha-3 heavy chain |
| Antigen Species | Human |
| Gene Name | ITGA3 |
| Gene ID | |
| Protein Name | Integrin alpha-3 |
| Uniprot ID | |
| Function | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Molecular Weight | Theoretical: 93/114 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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