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Anti-PAFAHG Polyclonal Antibody
😃Good
Catalog No. TMAB-09925
Anti-PAFAHG Polyclonal Antibody is a Rabbit antibody targeting PAFAHG. Anti-PAFAHG Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-PAFAHG Polyclonal Antibody
Anti-PAFAHG Polyclonal Antibody
😃Good
Catalog No. TMAB-09925
Anti-PAFAHG Polyclonal Antibody is a Rabbit antibody targeting PAFAHG. Anti-PAFAHG Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PAFAHG Polyclonal Antibody is a Rabbit antibody targeting PAFAHG. Anti-PAFAHG Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | In the adult, expressed in brain, skeletal muscle, kidney, thymus, spleen, colon, testis, ovary and peripheral blood leukocytes. In the fetus, highest expression occurs in brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The platelet activating factor (PAF) acetylhydrolases catalyze hydrolysis of the sn-2 ester bond of PAF and related pro-inflammatory phospholipids and thus attenuate their bioactivity. The family of PAF acetylhydrolases includes one secreted plasma isozyme and two intracellular isozymes. The intracellular isozymes are distinguished by differences in their primary sequence, tissue localization, subunit composition and substrate preferences. The most thoroughly characterized intracellular isoform, PAFAH1B, is a heterotrimeric protein expressed in brain tissue and plays and important role in brain development and function. PAFAH1B is comprised of a regulatory subunit (LIS1) and two homologous (63% identity) catalytic subunits (PAFAH1B2 and PAFAH1B3), which harbor all the activity of the enzyme. The PAFAH1B2 and PAFAH1B3 subunits readily associate with very high affinity to form heterodimers, and this dimerization is essential for both stability and catalytic activity. PAFAH1B3 is also commonly known as PAFAH1B 29kDa subunit, PAFAH1B subunit or PAFAH1B subunit α1. |
| Immunogen | KLH conjugated synthetic peptide: human PAFAH1B3/PAFAHG |
| Antigen Species | Human |
| Gene Name | PAFAH1B3 |
| Gene ID | |
| Protein Name | Platelet-activating factor acetylhydrolase IB subunit alpha1 |
| Uniprot ID | |
| Function | Inactivates paf by removing the acetyl group at the sn-2position. This is a catalytic subunit. Plays an important roleduring the development of brain. |
| Molecular Weight | Theoretical: 26 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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