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Anti-Phospho-A Raf (Ser214) Polyclonal Antibody
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Catalog No. TMAB-10281
Anti-Phospho-A Raf (Ser214) Polyclonal Antibody is a Rabbit antibody targeting Phospho-A Raf (Ser214). Anti-Phospho-A Raf (Ser214) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-A Raf (Ser214) Polyclonal Antibody
Anti-Phospho-A Raf (Ser214) Polyclonal Antibody
😃Good
Catalog No. TMAB-10281
Anti-Phospho-A Raf (Ser214) Polyclonal Antibody is a Rabbit antibody targeting Phospho-A Raf (Ser214). Anti-Phospho-A Raf (Ser214) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-Phospho-A Raf (Ser214) Polyclonal Antibody is a Rabbit antibody targeting Phospho-A Raf (Ser214). Anti-Phospho-A Raf (Ser214) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Predominantly in urogenital tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human A Raf around the phosphorylation site of Ser214 |
| Antigen Species | Human |
| Gene Name | ARAF |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase A-Raf |
| Uniprot ID | |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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