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Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody

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Catalog No. TMAB-10857

Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL7R (Tyr449). Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody can be used in WB,FCM.

Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody

Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody

😃Good
Catalog No. TMAB-10857
Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL7R (Tyr449). Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL7R (Tyr449). Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 2μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted and Cell membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human IL-7Ra around the phosphorylation site of Tyr449
Antigen Species
Human
Gene Name
IL7R
Gene ID
3575
Protein Name
Interleukin-7 receptor subunit alpha
Uniprot ID
P16871
Function
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Chemical Properties
Molecular WeightTheoretical: 48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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