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Anti-ETBR Polyclonal Antibody
Catalog No. TMAB-05713 Copy Product Info
🥰Excellent
Anti-ETBR Polyclonal Antibody is a Rabbit antibody targeting ETBR. Anti-ETBR Polyclonal Antibody can be used in WB.
Anti-ETBR Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-05713
Anti-ETBR Polyclonal Antibody is a Rabbit antibody targeting ETBR. Anti-ETBR Polyclonal Antibody can be used in WB.
Anti-ETBR Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ETBR Polyclonal Antibody is a Rabbit antibody targeting ETBR. Anti-ETBR Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Sample: HepG2 (Human) Cell Lysate at 30 μg Primary: Anti-ETBR (TMAB-05713) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 55 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding - suggesting that these two variants are functionally distinct. |
| Immunogen | KLH conjugated synthetic peptide: human EDNRB |
| Antigen Species | Human |
| Gene Name | EDNRB |
| Gene ID | |
| Protein Name | Endothelin receptor type B |
| Uniprot ID | |
| Function | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Molecular Weight | Theoretical: 50 kDa. Actual: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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