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Anti-IFNL2 Monoclonal Antibody (Alias: Interleukin-28A, Interferon lambda-2, Cytokine Zcyto20)
Catalog No. TMAZ-0009 Copy Product Info
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Anti-IFNL2 Monoclonal Antibody is a humanized rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA,FCM.
Anti-IFNL2 Monoclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAZ-0009
Alias Interleukin-28A, Interferon lambda-2, Cytokine Zcyto20
Anti-IFNL2 Monoclonal Antibody is a humanized rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA,FCM.
Anti-IFNL2 Monoclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-IFNL2 Monoclonal Antibody is a humanized rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA,FCM. |
| Synonyms | Interleukin-28A, Interferon lambda-2, Cytokine Zcyto20 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of IFNL2 overexpressed 410F cells with TMAZ-0009, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IFNL2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression |
| Conjucates | Unconjugated |
| Others Formats | Biotin |
| Antibody Types Available | 2 |
| Immunogen | IFNL2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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