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Anti-MAP3K13/LZK Polyclonal Antibody

Catalog No. TMAB-08567 Copy Product Info
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Anti-MAP3K13/LZK Polyclonal Antibody is a Rabbit antibody targeting MAP3K13/LZK. Anti-MAP3K13/LZK Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-MAP3K13/LZK Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08567

Anti-MAP3K13/LZK Polyclonal Antibody is a Rabbit antibody targeting MAP3K13/LZK. Anti-MAP3K13/LZK Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-MAP3K13/LZK Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MAP3K13/LZK Polyclonal Antibody is a Rabbit antibody targeting MAP3K13/LZK. Anti-MAP3K13/LZK Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Cow, Orangutan)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MAP3 k13) Polyclonal Antibody, Unconjugated (TMAB-08567) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
2. Sample: K562 Cell (Human) Lysate at 40 μg
Primary: Anti-MAP3 k13/LZK (TMAB-08567) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 108 kD
Observed band size: 108 kD
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Membrane.
Tissue SpecificityExpressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MAP3K13/LZK
Antigen Species
Human
Gene Name
Map3k13
Gene ID
Protein Name
Mitogen-activated protein kinase kinase kinase 13
Uniprot ID
Function
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Chemical Properties
Molecular WeightTheoretical: 108 kDa. Actual: 108 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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