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Anti-FAM20C Polyclonal Antibody

Catalog No. TMAB-05855 Copy Product Info
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Anti-FAM20C Polyclonal Antibody is a Rabbit antibody targeting FAM20C. Anti-FAM20C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FAM20C Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05855

Anti-FAM20C Polyclonal Antibody is a Rabbit antibody targeting FAM20C. Anti-FAM20C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FAM20C Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FAM20C Polyclonal Antibody is a Rabbit antibody targeting FAM20C. Anti-FAM20C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Horse,Sheep,Monkey)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (FAM20C) Polyclonal Antibody, Unconjugated (TMAB-05855) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityWidely expressed.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe FAM20 proteins are a family of secreted proteins that regulate differentiation and function of hematopoietic and other tissues. FAM20C, also known as DMP4 (Dentin matrix protein 4), is a 570 amino acid secreted protein that binds calcium and may play a role in dentin mineralization. Defects in the gene encoding FAM20C are the cause of Raine syndrome (Lethal osteosclerotic bone dysplasia), an autosomal recessive osteosclerotic bone dysplasia, that is characterized by generalized osteosclerosis, microencephaly and craniofacial dysplasia. Usually, affected individuals survive only days or weeks. The mutations of the FAM20C gene include four nonsynomous base changes and four splice-site changes that have a detrimental affect on splicing.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FAM20C
Antigen Species
Human
Gene Name
FAM20C
Gene ID
Protein Name
Extracellular serine/threonine protein kinase FAM20C
Uniprot ID
Function
Calcium-binding protein which may play a role in dentin mineralization.
Chemical Properties
Molecular WeightTheoretical: 64 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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