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Anti-Transglutaminase 6 Polyclonal Antibody
😃Good
Catalog No. TMAB-13736
Anti-Transglutaminase 6 Polyclonal Antibody is a Rabbit antibody targeting Transglutaminase 6. Anti-Transglutaminase 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Transglutaminase 6 Polyclonal Antibody
Anti-Transglutaminase 6 Polyclonal Antibody
😃Good
Catalog No. TMAB-13736
Anti-Transglutaminase 6 Polyclonal Antibody is a Rabbit antibody targeting Transglutaminase 6. Anti-Transglutaminase 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Transglutaminase 6 Polyclonal Antibody is a Rabbit antibody targeting Transglutaminase 6. Anti-Transglutaminase 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist. |
| Immunogen | KLH conjugated synthetic peptide: human TGase6/Transglutaminase 6 |
| Antigen Species | Human |
| Gene Name | TGM6 |
| Gene ID | |
| Protein Name | Protein-glutamine gamma-glutamyltransferase 6 |
| Uniprot ID | |
| Function | Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. |
| Molecular Weight | Theoretical: 79 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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