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Anti-Transglutaminase 6 Polyclonal Antibody
Catalog No. TMAB-13736 Copy Product Info
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Anti-Transglutaminase 6 Polyclonal Antibody is a Rabbit antibody targeting Transglutaminase 6. Anti-Transglutaminase 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Transglutaminase 6 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13736
Anti-Transglutaminase 6 Polyclonal Antibody is a Rabbit antibody targeting Transglutaminase 6. Anti-Transglutaminase 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Transglutaminase 6 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-Transglutaminase 6 Polyclonal Antibody is a Rabbit antibody targeting Transglutaminase 6. Anti-Transglutaminase 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Cow,Horse,Sheep) |
| Verified Activity | Tissue/cell: Rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-TGM6 Polyclonal Antibody, Unconjugated (TMAB-13736) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist. |
| Immunogen | KLH conjugated synthetic peptide: human TGase6/Transglutaminase 6 |
| Antigen Species | Human |
| Gene Name | TGM6 |
| Gene ID | |
| Protein Name | Protein-glutamine gamma-glutamyltransferase 6 |
| Uniprot ID | |
| Function | Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. |
| Molecular Weight | Theoretical: 79 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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