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Anti-Dermokine beta Polyclonal Antibody
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Catalog No. TMAB-05093
Anti-Dermokine beta Polyclonal Antibody is a Rabbit antibody targeting Dermokine beta. Anti-Dermokine beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Dermokine beta Polyclonal Antibody
Anti-Dermokine beta Polyclonal Antibody
😃Good
Catalog No. TMAB-05093
Anti-Dermokine beta Polyclonal Antibody is a Rabbit antibody targeting Dermokine beta. Anti-Dermokine beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Dermokine beta Polyclonal Antibody is a Rabbit antibody targeting Dermokine beta. Anti-Dermokine beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expressed in epidermis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Dermokine, also known as DMKN, ZD52F10 or UNQ729, is a 476 amino acid secreted protein that belongs to the dermokine family and exists as 15 alternatively spliced isoforms, the most notable of which are designated å and ∫. Existing as a homooligomer that can either homodimerize or homotrimerize, Dermokine is expressed in the epidermis, as well as in the epithelia of the lung and small intestine where it is thought to function as a regulator of keratinocyte differentiation, possibly playing a role in inflammatory responses. The gene encoding Dermokine maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). |
| Immunogen | KLH conjugated synthetic peptide: human Dermokine beta |
| Antigen Species | Human |
| Gene Name | DMKN |
| Gene ID | |
| Protein Name | Dermokine |
| Uniprot ID | |
| Function | May act as a soluble regulator of keratinocyte differentiation (Potential). |
| Molecular Weight | Theoretical: 45 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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