Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityAntigen DetailsChemical infoStorage&SolubilityCalculator

Anti-GPR40 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-06715

Anti-GPR40 Polyclonal Antibody 2 is a Rabbit antibody targeting GPR40. Anti-GPR40 Polyclonal Antibody 2 can be used in WB.

Anti-GPR40 Polyclonal Antibody 2

Anti-GPR40 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-06715
Anti-GPR40 Polyclonal Antibody 2 is a Rabbit antibody targeting GPR40. Anti-GPR40 Polyclonal Antibody 2 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Instruction Manual of Detection Antibody

Product Introduction

Bioactivity
Description
Anti-GPR40 Polyclonal Antibody 2 is a Rabbit antibody targeting GPR40. Anti-GPR40 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
Tissue SpecificityExpressed abundantly in pancreatic beta cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Concentration1mg/ml
Research BackgroundG protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse GPR40
Antigen Species
Mouse
Gene Name
FFAR1
Gene ID
233081
Protein Name
Free fatty acid receptor 1
Uniprot ID
Q76JU9
Function
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-GPR40 Polyclonal Antibody 2 | purchase Anti-GPR40 Polyclonal Antibody 2 | Anti-GPR40 Polyclonal Antibody 2 cost | order Anti-GPR40 Polyclonal Antibody 2 | Anti-GPR40 Polyclonal Antibody 2 molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.