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Anti-ALAD Polyclonal Antibody

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Catalog No. TMAB-02424

Anti-ALAD Polyclonal Antibody is a Rabbit antibody targeting ALAD. Anti-ALAD Polyclonal Antibody can be used in WB.

Anti-ALAD Polyclonal Antibody

Anti-ALAD Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-02424
Anti-ALAD Polyclonal Antibody is a Rabbit antibody targeting ALAD. Anti-ALAD Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ALAD Polyclonal Antibody is a Rabbit antibody targeting ALAD. Anti-ALAD Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Rat,Cow,Sheep,Dog,Rabbit,Horse,Human)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with ALAD polyclonal antibody, unconjugated (TMAB-02424) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCatalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP). AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ALAD
Antigen Species
Human
Gene Name
ALAD
Gene ID
Protein Name
delta-aminolevulinic acid dehydratase
Uniprot ID
Function
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
Chemical Properties
Molecular WeightTheoretical: 36 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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