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Anti-GLTSCR2 Polyclonal Antibody
Catalog No. TMAB-06530 Copy Product Info
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Anti-GLTSCR2 Polyclonal Antibody is a Rabbit antibody targeting GLTSCR2. Anti-GLTSCR2 Polyclonal Antibody can be used in WB.
Anti-GLTSCR2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06530
Anti-GLTSCR2 Polyclonal Antibody is a Rabbit antibody targeting GLTSCR2. Anti-GLTSCR2 Polyclonal Antibody can be used in WB.
Anti-GLTSCR2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-GLTSCR2 Polyclonal Antibody is a Rabbit antibody targeting GLTSCR2. Anti-GLTSCR2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Sheep) |
| Verified Activity | 1. Sample: Pancreas (Mouse) Lysate at 40 μg Primary: Anti-GLTSCR2 (TMAB-06530) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD 2. Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human HeLa cell lysates Primary: Anti-GLTSCR2 (TMAB-06530) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 65 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus; nucleolus. |
| Tissue Specificity | Expressed at high levels in heart and pancreas, moderate levels in placenta, liver, skeletal muscle, and kidney, and low levels in brain and lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is inactivated in a wide variety of tumors. Protein interacting with PTEN carboxyl terminus 1 (PICT-1), also designated p60 or Glioma tumor suppressor candidate region gene 2 protein, binds to the C-terminus of PTEN and regulates its turnover. Five Ser/Thr residues within the C-terminal segment of PTEN, including Ser-380, are phosphorylated upon binding of PTEN to PICT-1 and may contribute to the stabilization of PTEN. PICT-1 is localized to the nucleus and/or nucleolus and is highly expressed in pancreas and heart, but can also be detected in liver, skeletal muscle, placenta and kidney. PICT-1 also interacts with herpes simplex virus 1 regulatory proteins ICP22 and ICP0. The tumor suppressor GLTSCR2 gene, which encodes PICT-1, is located in a 150-kb minimal common deletion region for human gliomas, especially oligodendrogliomas, and maps to human chromosome 19q13.3. |
| Immunogen | KLH conjugated synthetic peptide: human GLTSCR2/PICT1 |
| Antigen Species | Human |
| Gene Name | NOP53 |
| Gene ID | |
| Protein Name | Ribosome biogenesis protein NOP53 |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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