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Cyclo(Ala-Gly) (Synonyms: Cyclo(L-Ala-L-Gly), (S)-3-methylpiperazine-2,5-dione)

Name: Cyclo(Ala-Gly)
Brand: TargetMol
SKU: T13629
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T13629 Copy Product Info

Purity: 99.93%

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Cyclo(Ala-Gly) is a natural cyclic dipeptide from the endophytic fungus Aspergillus fumigatus, with low toxicity (LC50 > 100 μg/mL) to Artemia salina.

Cyclo(Ala-Gly)

Copy Product Info

🥰Excellent

Catalog No. T13629

Synonyms Cyclo(L-Ala-L-Gly), (S)-3-methylpiperazine-2,5-dione

Cyclo(Ala-Gly) is a natural cyclic dipeptide from the endophytic fungus Aspergillus fumigatus, with low toxicity (LC50 > 100 μg/mL) to Artemia salina.

Cas No. 4526-77-6

Pack Size	Price	USA Stock	Global Stock	Quantity
25 mg	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.93%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Cyclo(Ala-Gly) is a natural cyclic dipeptide from the endophytic fungus Aspergillus fumigatus, with low toxicity (LC50 > 100 μg/mL) to Artemia salina.
Synonyms	Cyclo(L-Ala-L-Gly), (S)-3-methylpiperazine-2,5-dione

Chemical Properties

Molecular Weight	128.13
Formula	C₅H₈N₂O₂
Cas No.	4526-77-6
Smiles	C[C@H]1C(=O)NCC(=O)N1
Relative Density.	1.149g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 18 mg/mL (140.48 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (15.61 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.8046 mL	39.0229 mL	78.0457 mL	390.2287 mL
5 mM	1.5609 mL	7.8046 mL	15.6091 mL	78.0457 mL
10 mM	0.7805 mL	3.9023 mL	7.8046 mL	39.0229 mL
20 mM	0.3902 mL	1.9511 mL	3.9023 mL	19.5114 mL
50 mM	0.1561 mL	0.7805 mL	1.5609 mL	7.8046 mL
100 mM	0.0780 mL	0.3902 mL	0.7805 mL	3.9023 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc