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Anti-Phospho-MCAK (Ser95) Polyclonal Antibody
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Catalog No. TMAB-10954
Anti-Phospho-MCAK (Ser95) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MCAK (Ser95). Anti-Phospho-MCAK (Ser95) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-MCAK (Ser95) Polyclonal Antibody
Anti-Phospho-MCAK (Ser95) Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-10954
Anti-Phospho-MCAK (Ser95) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MCAK (Ser95). Anti-Phospho-MCAK (Ser95) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-Phospho-MCAK (Ser95) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MCAK (Ser95). Anti-Phospho-MCAK (Ser95) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Horse,Rabbit) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (phospho-MCAK (Ser95)) Polyclonal Antibody, Unconjugated (TMAB-10954) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm > cytoskeleton. Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2. |
| Tissue Specificity | Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Immunogen | KLH conjugated synthesised phosphopeptide: human MCAK around the phosphorylation site of Ser95 |
| Antigen Species | Human |
| Gene Name | Kif2c |
| Gene ID | |
| Protein Name | Kinesin-like protein KIF2C |
| Uniprot ID | |
| Function | Promotes ATP-dependent removal of tubulin dimers from microtubules. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. |
| Molecular Weight | Theoretical: 81 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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