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Anti-NPDC1 Polyclonal Antibody
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Catalog No. TMAB-09586
Anti-NPDC1 Polyclonal Antibody is a Rabbit antibody targeting NPDC1. Anti-NPDC1 Polyclonal Antibody can be used in WB.
Anti-NPDC1 Polyclonal Antibody
Anti-NPDC1 Polyclonal Antibody
😃Good
Catalog No. TMAB-09586
Anti-NPDC1 Polyclonal Antibody is a Rabbit antibody targeting NPDC1. Anti-NPDC1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-NPDC1 Polyclonal Antibody is a Rabbit antibody targeting NPDC1. Anti-NPDC1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass membrane protein (Potential). |
| Tissue Specificity | Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human. |
| Immunogen | KLH conjugated synthetic peptide: human NPDC1 |
| Antigen Species | Human |
| Gene Name | NPDC1 |
| Gene ID | |
| Protein Name | Neural proliferation differentiation and control protein 1 |
| Uniprot ID | |
| Function | Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation. |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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