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Anti-NPDC1 Polyclonal Antibody

Catalog No. TMAB-09586 Copy Product Info
🥰Excellent
Anti-NPDC1 Polyclonal Antibody is a Rabbit antibody targeting NPDC1. Anti-NPDC1 Polyclonal Antibody can be used in WB.

Anti-NPDC1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09586

Anti-NPDC1 Polyclonal Antibody is a Rabbit antibody targeting NPDC1. Anti-NPDC1 Polyclonal Antibody can be used in WB.

Anti-NPDC1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NPDC1 Polyclonal Antibody is a Rabbit antibody targeting NPDC1. Anti-NPDC1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat)
Verified Activity
1. Sample: Large intestine (mouse) Lysate at 40 μg
Primary: Anti-NPDC1 (TMAB-09586) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kD
Observed band size: 31 kD
2. Sample: Uterus (mouse) Lysate at 40 μg
Primary: Anti-NPDC1 (TMAB-09586) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kD
Observed band size: 31 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass membrane protein (Potential).
Tissue SpecificityStrongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NPDC1
Antigen Species
Human
Gene Name
NPDC1
Gene ID
56654
Protein Name
Neural proliferation differentiation and control protein 1
Uniprot ID
Q9NQX5
Function
Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation.
Chemical Properties
Molecular WeightTheoretical: 31 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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