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Anti-TCN2 Antibody (8U681) (Synonyms: transcobalamin II, Tcn-2, AW208754)

Catalog No. TMAY-03406 Copy Product Info
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Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA.

Anti-TCN2 Antibody (8U681)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03406
Synonyms transcobalamin II, Tcn-2, AW208754

Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA.

Anti-TCN2 Antibody
(8U681)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA.
Synonymstranscobalamin II, Tcn-2, AW208754
Ig Type
Rabbit IgG
Clone
8U681
Reactivity
Mouse
Specificity
Mouse Transcobalamin II
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse TCN2 (rM TCN2; TMPY-02192; O88968; Met1-Trp430).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTranscobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 2 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse TCN2 protein (TMPY-02192)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Keywords

AW-208754AW 208754
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