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Anti-TCN2 Antibody (8U681)
😃Good
Catalog No. TMAY-03406
Alias transcobalamin II, Tcn-2, AW208754
Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA.
Anti-TCN2 Antibody (8U681)
Anti-TCN2 Antibody (8U681)
😃Good
Catalog No. TMAY-03406Alias transcobalamin II, Tcn-2, AW208754
Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $270 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA. |
| Synonyms | transcobalamin II, Tcn-2, AW208754 |
| Ig Type | Rabbit IgG |
| Clone | 8U681 |
| Reactivity | Mouse |
| Specificity | Mouse Transcobalamin II |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TCN2 (rM TCN2; TMPY-02192; O88968; Met1-Trp430). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 2 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse TCN2 protein (TMPY-02192) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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