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Anti-ABH8 Polyclonal Antibody

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Catalog No. TMAB-02167
Alias S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, Alkylated DNA repair protein alkB homolog 8, ALKBH8, ALKB8_HUMAN, AlkB homologue 8, alkB alkylation repair homolog 8(E. coli), alkB alkylation repair homolog 8, ABH8

Anti-ABH8 Polyclonal Antibody is a Rabbit antibody targeting ABH8. Anti-ABH8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-ABH8 Polyclonal Antibody

Anti-ABH8 Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-02167Alias S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, Alkylated DNA repair protein alkB homolog 8, ALKBH8, ALKB8_HUMAN, AlkB homologue 8, alkB alkylation repair homolog 8(E. coli), alkB alkylation repair homolog 8, ABH8
Anti-ABH8 Polyclonal Antibody is a Rabbit antibody targeting ABH8. Anti-ABH8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ABH8 Polyclonal Antibody is a Rabbit antibody targeting ABH8. Anti-ABH8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
SynonymsS-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, Alkylated DNA repair protein alkB homolog 8, ALKBH8, ALKB8_HUMAN, AlkB homologue 8, alkB alkylation repair homolog 8(E. coli), alkB alkylation repair homolog 8, ABH8
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABH8) Polyclonal Antibody, Unconjugated (TMAB-02167) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Note=Predominantlycytoplasmic.
Tissue SpecificityWidely expressed, with highest expression inspleen, followed by pancreas and lung.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCatalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ABH8/ALKBH8
Antigen Species
Human
Gene Name
ALKBH8
Gene ID
Protein Name
Alkylated DNA repair protein alkB homolog 8
Uniprot ID
Function
Catalyzes the methylation of 5-carboxymethyl uridine to5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in tRNA. Catalyzes the last step in the formation of5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in target tRNA. Has a preference for tRNA(Arg) andtRNA(Glu), and does not bind tRNA(Lys). Required for normalsurvival after DNA damage. May inhibit apoptosis and promote cellsurvival and angiogenesis.
Chemical Properties
Molecular WeightTheoretical: 75 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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