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Anti-MYCBPAP Polyclonal Antibody

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Catalog No. TMAB-09140

Anti-MYCBPAP Polyclonal Antibody is a Rabbit antibody targeting MYCBPAP. Anti-MYCBPAP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-MYCBPAP Polyclonal Antibody

Anti-MYCBPAP Polyclonal Antibody

😃Good
Catalog No. TMAB-09140
Anti-MYCBPAP Polyclonal Antibody is a Rabbit antibody targeting MYCBPAP. Anti-MYCBPAP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MYCBPAP Polyclonal Antibody is a Rabbit antibody targeting MYCBPAP. Anti-MYCBPAP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Membrane. Colocalizes with MYCBP in the cytoplasm.
Tissue SpecificityExpressed specifically in testis.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundAMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MYCBPAP
Antigen Species
Human
Gene Name
MYCBPAP
Gene ID
84073
Protein Name
MYCBP-associated protein
Uniprot ID
Q8TBZ2
Function
May play a role in spermatogenesis. May be involved in synaptic processes.
Chemical Properties
Molecular WeightTheoretical: 108 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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