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Anti-TLR7 Polyclonal Antibody 2
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Catalog No. TMAB-13574
Anti-TLR7 Polyclonal Antibody 2 is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody 2 can be used in WB,FCM.
Anti-TLR7 Polyclonal Antibody 2
Anti-TLR7 Polyclonal Antibody 2
Copy Product Info😃Good
Catalog No. TMAB-13574
Anti-TLR7 Polyclonal Antibody 2 is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody 2 can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-TLR7 Polyclonal Antibody 2 is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody 2 can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse) |
| Verified Activity | 1. Sample: Lane 1: Rat Spleen tissue lysates Lane 2: Rat Lung tissue lysates Lane 3: Recombinant human TLR7 protein (24-348/1049aa) 50 ng Primary: Anti-TLR7 (TMAB-13574) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 121 kDa Observed band size: 165, 40 kDa 2. The THP-1 (H) cells were incubated in 5% BSA to block non-specific protein-protein interactions (30 min at r. T.). Primary Antibody (green): Rabbit Anti-TLR7 antibody (TMAB-13574): 1 μg/10^6 cells; Isotype Control (orange): Rabbit IgG. Blank control (black): PBS. Acquisition of 20,000 events was performed. |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. |
| Tissue Specificity | Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
| Immunogen | Recombinant Protein: human TLR7 protein |
| Antigen Species | Human |
| Gene Name | TLR7 |
| Gene ID | |
| Protein Name | Toll-like receptor 7 |
| Uniprot ID | |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
| Molecular Weight | Theoretical: 121 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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