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Anti-TLR7 Polyclonal Antibody 2

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Catalog No. TMAB-13574

Anti-TLR7 Polyclonal Antibody 2 is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody 2 can be used in WB,FCM.

Anti-TLR7 Polyclonal Antibody 2

Anti-TLR7 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-13574
Anti-TLR7 Polyclonal Antibody 2 is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody 2 can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TLR7 Polyclonal Antibody 2 is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody 2 can be used in WB,FCM.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse)
Application
Recommended Dose
WB: 1:500-2000; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Tissue SpecificityDetected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Antigen Details
Immunogen
Recombinant Protein: human TLR7 protein
Antigen Species
Human
Gene Name
TLR7
Gene ID
Protein Name
Toll-like receptor 7
Uniprot ID
Function
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Chemical Properties
Molecular WeightTheoretical: 121 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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