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Anti-GW182 Polyclonal Antibody
Catalog No. TMAB-06858 Copy Product Info
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Anti-GW182 Polyclonal Antibody is a Rabbit antibody targeting GW182. Anti-GW182 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GW182 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06858
Anti-GW182 Polyclonal Antibody is a Rabbit antibody targeting GW182. Anti-GW182 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GW182 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GW182 Polyclonal Antibody is a Rabbit antibody targeting GW182. Anti-GW182 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded Rat Stomach; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with GW182 Polyclonal Antibody, Unconjugated (TMAB-06858) at 1: 200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm > P-body. Mammalian P-bodies are also known as GW bodies. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human GW182 |
| Antigen Species | Human |
| Gene Name | TNRC6A |
| Gene ID | |
| Protein Name | Trinucleotide repeat-containing gene 6A protein |
| Uniprot ID | |
| Function | Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. |
| Molecular Weight | Theoretical: 210 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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