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Anti-Hexokinase 2 Polyclonal Antibody
Catalog No. TMAB-07003 Copy Product Info
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Anti-Hexokinase 2 Polyclonal Antibody is a Rabbit antibody targeting Hexokinase 2. Anti-Hexokinase 2 Polyclonal Antibody can be used in WB.
Anti-Hexokinase 2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07003
Anti-Hexokinase 2 Polyclonal Antibody is a Rabbit antibody targeting Hexokinase 2. Anti-Hexokinase 2 Polyclonal Antibody can be used in WB.
Anti-Hexokinase 2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-Hexokinase 2 Polyclonal Antibody is a Rabbit antibody targeting Hexokinase 2. Anti-Hexokinase 2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Sample: Skeletal muscle (Mouse) Lysate at 40 μg Primary: Anti-Hexokinase 2 (TMAB-07003) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 101 kD Observed band size: 101 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding. |
| Tissue Specificity | Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose-6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HXK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines. HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues. Of the hexokinases, HXK III has the highest affinity for glucose. Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, determining the “set point” for insulin secretion. |
| Immunogen | KLH conjugated synthetic peptide: human Hexokinase 2 |
| Antigen Species | Human |
| Gene Name | HK2 |
| Gene ID | |
| Protein Name | Hexokinase-2 |
| Uniprot ID | |
| Function | Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. |
| Molecular Weight | Theoretical: 101 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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