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Anti-GCOM1/GRINL1A Polyclonal Antibody

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Catalog No. TMAB-06396

Anti-GCOM1/GRINL1A Polyclonal Antibody is a Rabbit antibody targeting GCOM1/GRINL1A. Anti-GCOM1/GRINL1A Polyclonal Antibody can be used in WB.

Anti-GCOM1/GRINL1A Polyclonal Antibody

Anti-GCOM1/GRINL1A Polyclonal Antibody

😃Good
Catalog No. TMAB-06396
Anti-GCOM1/GRINL1A Polyclonal Antibody is a Rabbit antibody targeting GCOM1/GRINL1A. Anti-GCOM1/GRINL1A Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GCOM1/GRINL1A Polyclonal Antibody is a Rabbit antibody targeting GCOM1/GRINL1A. Anti-GCOM1/GRINL1A Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Cow,Horse,Rabbit,Sheep)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GCOM1
Antigen Species
Human
Gene Name
POLR2M
Gene ID
81488
Protein Name
DNA-directed RNA polymerase II subunit GRINL1A
Uniprot ID
P0CAP2
Chemical Properties
Molecular WeightTheoretical: 62 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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