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Anti-TNFRSF10A Polyclonal Antibody 2
Catalog No. TMAB-13632 Copy Product Info
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Anti-TNFRSF10A Polyclonal Antibody 2 is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody 2 can be used in WB.
Anti-TNFRSF10A Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-13632
Anti-TNFRSF10A Polyclonal Antibody 2 is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody 2 can be used in WB.
Anti-TNFRSF10A Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-TNFRSF10A Polyclonal Antibody 2 is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | Sample: Lane 1: Human Jurkat cell lysates Lane 2: Human A549 cell lysates Lane 3: Human HUVEC cell lysates Lane 4: Human HeLa cell lysates Primary: Anti-TNFRSF10A (TMAB-13632) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kDa Observed band size: 60 kDa |
| Application | |
| Recommended Dose | WB: 1:200-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant Protein: human TNFRSF10A protein |
| Antigen Species | Human |
| Gene Name | TNFRSF10A |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 10A |
| Uniprot ID | |
| Function | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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