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Anti-hUPF2/RENT2 Polyclonal Antibody

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Catalog No. TMAB-07456

Anti-hUPF2/RENT2 Polyclonal Antibody is a Rabbit antibody targeting hUPF2/RENT2. Anti-hUPF2/RENT2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-hUPF2/RENT2 Polyclonal Antibody

Anti-hUPF2/RENT2 Polyclonal Antibody

😃Good
Catalog No. TMAB-07456
Anti-hUPF2/RENT2 Polyclonal Antibody is a Rabbit antibody targeting hUPF2/RENT2. Anti-hUPF2/RENT2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-hUPF2/RENT2 Polyclonal Antibody is a Rabbit antibody targeting hUPF2/RENT2. Anti-hUPF2/RENT2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Cow,Rabbit,Sheep,Ferret,Gorilla,Opossum,Platypus)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm > perinuclear region.
Tissue SpecificityUbiquitous.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human hUPF2/RENT2
Antigen Species
Human
Gene Name
UPF2
Gene ID
26019
Protein Name
Regulator of nonsense transcripts 2
Uniprot ID
Q9HAU5
Function
Part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA.
Chemical Properties
Molecular WeightTheoretical: 148 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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