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Anti-SIRT5 Polyclonal Antibody
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Catalog No. TMAB-12818
Anti-SIRT5 Polyclonal Antibody is a Rabbit antibody targeting SIRT5. Anti-SIRT5 Polyclonal Antibody can be used in WB,FCM.
Anti-SIRT5 Polyclonal Antibody
Anti-SIRT5 Polyclonal Antibody
😃Good
Catalog No. TMAB-12818
Anti-SIRT5 Polyclonal Antibody is a Rabbit antibody targeting SIRT5. Anti-SIRT5 Polyclonal Antibody can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SIRT5 Polyclonal Antibody is a Rabbit antibody targeting SIRT5. Anti-SIRT5 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion matrix. Mitochondrion intermembrane space. |
| Tissue Specificity | Widely expressed. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Sirtuins (SIRT1-7) are human homologs of the yeast Sir2 (silent information regulator-2) protein and are divided into four main classes: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. In S. cerevisiae, Sir2 deacetylates histones in an NAD-dependent manner, which regulates silencing at the telomeric, rDNA (ribosomal RNA) and silent mating-type loci. The human SIRT proteins are NAD-dependent deacetylases that act as intracellular regulators and are thought to have ribosyltransferase activity. SIRT5 (NAD-dependent deacetylase sirtuin-5), also known as SIR2L5, is a 310 amino acid member of the class III sirtuins. Localized to mitochrondria and expressed throughout the body, SIRT5 is an NAD-dependent deacetylase that may link metabolic aging processes in humans. SIRT5 contains one deacetylase-sirtuin-type domain and can be deactivated by suramin, a drug that blocks the binding of various growth factors. Two isoforms of SIRT5 exist due to alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human SIRT5 |
| Antigen Species | Human |
| Gene Name | SIRT5 |
| Gene ID | |
| Protein Name | NAD-dependent protein deacylase sirtuin-5, mitochondrial |
| Uniprot ID |
| Molecular Weight | Theoretical: 30 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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