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Anti-C1 Inactivator Polyclonal Antibody

Catalog No. TMAB-03284 Copy Product Info
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Anti-C1 Inactivator Polyclonal Antibody is a Rabbit antibody targeting C1 Inactivator. Anti-C1 Inactivator Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-C1 Inactivator Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-03284

Anti-C1 Inactivator Polyclonal Antibody is a Rabbit antibody targeting C1 Inactivator. Anti-C1 Inactivator Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-C1 Inactivator Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-C1 Inactivator Polyclonal Antibody is a Rabbit antibody targeting C1 Inactivator. Anti-C1 Inactivator Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,GuineaPig)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (C1 Inactivator) Polyclonal Antibody, Unconjugated (TMAB-03284) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundC1 Inactivator is a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SERPING1
Antigen Species
Human
Gene Name
SERPING1
Gene ID
Protein Name
Plasma protease C1 inhibitor
Uniprot ID
Function
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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