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Anti-C1 Inactivator Polyclonal Antibody

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Catalog No. TMAB-03284

Anti-C1 Inactivator Polyclonal Antibody is a Rabbit antibody targeting C1 Inactivator. Anti-C1 Inactivator Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-C1 Inactivator Polyclonal Antibody

Anti-C1 Inactivator Polyclonal Antibody

😃Good
Catalog No. TMAB-03284
Anti-C1 Inactivator Polyclonal Antibody is a Rabbit antibody targeting C1 Inactivator. Anti-C1 Inactivator Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-C1 Inactivator Polyclonal Antibody is a Rabbit antibody targeting C1 Inactivator. Anti-C1 Inactivator Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,GuineaPig)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundC1 Inactivator is a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SERPING1
Antigen Species
Human
Gene Name
SERPING1
Gene ID
Protein Name
Plasma protease C1 inhibitor
Uniprot ID
Function
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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